Osage National is a 27-hole layout located on a bend of the Osage River and US 54 in Lake of the Ozarks.

The course marches over bottomland and along ridges overlooking the Osage River with an unending variety of water hazards, including lakes, ponds, streams, and the River. Old-growth trees define the broad fairways with a healthy dose of sand bunkers, including long waste areas defending the landing zones off the tee and the greens. There are five sets of tees overall, yardages, and course/slope ratings for the various rotations from the tips: River-3,543 yards; Mountain-3,606 yards; Links-3,559 yards. River/Mountains-75.6/145, course/slope ratings; Links/River-75.6/141; Mountain/Links-74.7/141, designed in part by Arnold Palmer.