Otter Creek is located in Columbus, about 40 minutes south of Indianapolis, off I-65 to the east. It is in a predominantly natural setting surrounded by farmland and Clifty Creek on its northern border.

The course is through the rolling hills of southern Indiana, using the existing contours of the land instead of moving earth. There is a collection of challenging and unique holes with numerous water features and over 90 sand bunkers. There are five sets of tees overall, from the tips: the North/is 3,320 yards, West 3,621 yards, North/West 75.1/146, course/slope ratings, an original design by Robert Trent Jones, Sr., Rees Jones, and an update and reconfiguration by Billy Fuller and Tom Kite.